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Saturday, 17 May, 2008




Keeping you up to date with the latest clinical trial information

Growth Hormone Deficiency

Second University of Naples Growth Hormone Deficiency in Autoimmune Pituitary Disorders
Growth hormone (GH) is a polypeptide hormone consisting of 191 amino acids, synthesised, stored and secreted by somatotroph cells in the lateral wings of the anterior pituitary, in a gender- and age dependent manner.
Mehul Dattani Novel Insights into the Management of Growth Hormone Deficiency
Traditionally, short stature is defined as a height that lies more than two standard deviations (SD) below the mean for age compared with gender-specific standards based on an appropriate healthy population.
GH Treatment Psychometric properties of two measures of psychological well-being in adult growth hormone deficiency
The physical symptoms of adult growth hormone deficiency (GHD) include abnormal body composition with reduced lean body mass and increased central adiposity; reduced muscle strength and exercise performance
Newly FDA-approved drugs

Omnitrope (somatropin [rDNA origin]) for Injection
Approved: May 30, 2006 Company: Sandoz
Treatment for: Growth Disorders
Omnitrope is recombinant human growth hormone indicated for Approvals process long-term treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, and long-term replacement therapy in adults with growth hormone deficiency (GHD) of either childhood- or adult- onset etiology.
Guidelines Watch change
A round up of the latest Clinical Guidelines from the National Guideline Clearinghouse (NGC)

GROWTH HORMONE DEFICIENCY

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline
The Endocrine Society - Disease Specific Society. 2006. 33 pages. NGC:004980

Human growth hormone (somatropin) in adults with growth hormone deficiency
National Institute for Health and Clinical Excellence - National Government Agency [Non-U.S.]. 2003 Aug. 34 pages. NGC:004909.

National Guideline Clearinghouse

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